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LINKS TO INTERACTIVE 3-D STRUCTURES1 of IMMUNE EFFECTOR MOLECULES

ANTIBODY DOMAIN STRUCTURES MHC CLASS II: HUMAN (HLA-DP,DQ,DR) AND MOUSE (H-2A,E)
Human IgG1 Domain Animations Overview: HLA-DR1 + Flu virus hemagglutinin peptide
Overview: Human IgG1 (in sequence) Animation: HLA-DR1 + (Ala)13
VL-VH Domain Interactions HLA-DR1 Complex with Staph Enterotoxin B Super Antigen
CL-CH1 Domain Interactions + Interchain H-L Disulfide HLA-DR3 Complex with CLIP (Class II Associated Invariant Chain Peptide)
Hinge Region + Interchain H-H Disulfides HLA-DR1 Complex with CLIP
CH2-CH2 Domains + Carbohydrate Interactions T CELL RECEPTOR AND CO-RECEPTOR MOLECULES
CH3-CH3 Domain Interactions TCR Overview (in sequence)
ANTIBODY-ANTIGEN INTERACTIONS TCR Alpha/Beta Dimer
Monoclonal Fab/Hen Egg-White Lysozyme Complex TCR Interdomain Interactions
Two Monoclonal Fab/Hen Egg-White Lysozyme Complexes TCR Hypervariable Regions
Catalytic Antibody: Mouse Monoclonal Abzyme + Hapten TCR Antigen Binding Sites
MHC CLASS I: HUMAN (HLA-A,B,C) AND MOUSE (H-2K,D,L) TCR-Antigen-Class I Complex
Overview: HLA-Aw68.1 TARGETED PATHOGEN STRUCTURES
Animation: H-2Kb + SEV-9 Peptide
Flu Virus: Hemagglutinin (HA) Antigenic Structure
Dual Peptide Binding to H-2Kb: SEV-9 and OVA-8 Peptides
Human Immunodeficiency Virus (HIV): Protease + Inhibitor
TCR-Antigen-Class I Complex: TCR + H-2Kb + dEV8 MECHANISMS OF ANTIBODY AND T-CELL RECEPTOR DIVERSIFICATION
Antigen-Class I-CD8 Complex: HLA-A2 + Ag + CD8 Dimer V-J Joining: Junctional Diversification by Alternate DNA Joining
MHC HLA-B2705 bound to 3 Viral Peptides and 1 Self Peptide CYTOKINE AND CYTOKINE RECEPTOR STRUCTURES 
    Lymphotoxin/TNF Receptor Complex

LINKS TO OTHER INSTRUCTIONAL WEBPAGES

ADAPTIVE AND INNATE IMMUNE CELLS ANTIBODY-ANTIGEN INTERACTIONS
Leukocyte Subpopulations Scatchard Analysis of Antibody-Antigen Interactions (EXCEL)
Cell Analysis by Flowcytometry (FLASH ANIMATION)
  Cell Analysis by Fluorescence Activated Cell Sorting (FACS) (FLASH ANIMATION)

1The embedded 3-D macromolecular images displayed on this website are rendered by JSmol, an HTML5-compatible JavaScript framework supported by most web browsers.
Duane W. Sears
Revised: July 30, 2016