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O2 binding by Mb and Hb Conformational Flexibility of Hb and O2 Transport 2,3-BPG Binding Pocket of HbA
Myoglobin Heme O2-binding pocket
 

deoxyHbA to oxyHbA conformational switch
Roll mouse over the image below to switch between deoxyHb & oxyHb structure and function.

venous
to arterial blood O2 saturation shift.

Structures and O2-binding Functions of Hb Hemoglobin O2 Saturation Analysis (Excel Plots) Tutorials and Practice Quizzes

O2-induced 3-D shift in the Fe-Heme-His87 Compex in the Transition from deoxyHb to oxyHb.

Hemoglobin Saturation Analysis - Regulation  (Excel) 
Saturation, Hill, and Scatchard Graphical Analysis of Hb & Mb Oxygen Binding (Excel)
Oxygen Transport by Hb and Mb (CDF)
Rectilinear O2 Saturation Plot (CDF)
Rectilinear vs. Hill O2 Saturation Plot (CDF)
Hill O2 Saturation Plots (CDF)
PQ06 - Titration Analysis of Mb and Hb


Multivalent Ligand Binding
Diprotic Buffer Analysis: Length-dependent dicabroxylate anti-Cooperative titration
Diprotic Buffer Analysis: Two-step dicarboxylate equilibrium reactions
Overview of Multivalent Ligand Binding Interactions  (PDF)
Trivalent "Non-Interactive" Binding Equilibrium Reactions 
Trivalent Amino Acid "Non-Interactive" Ligand Binding (Excel)
Trivalent Amino Acids- Acid/Base Titration Analysis (CDF)
© Duane W. Sears, July 12, 2020