Human IgG1   Mouse Moves
Click here for an overview of the three-dimensional structure of human IgG1 antibodies.

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PDB chain designations
heavy chains:
:H & :I
light chains:
:L & :M
carbohydrates:
:C & :D
This model of human IgG1 was created by E. A. Padlin -- "Anatomy of the Antibody Molecule," Molecular Immunology 31:169 (1994) -- and the complete coordinates can be downloaded from the University of Massachusetts RasMol web site. Complete structural coordinates were generated by combining the Brookhaven X-ray coordinate files for the human IgG1 Fc (1fc2.pdb) and F(ab') (2ig2.pdb) fragments after symmetrically rotating the latter to produce the coordinates for bivalent F(ab')2 "fragment."
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© Sean R. Christensen & Duane W. Sears
August 3, 2012