Aspartate Transcarbamoylase: ATCase - (c3)2(r2)3 Reload
c3+/-   r2+/-
 
regulatory (r) subunits  
CTP -/+
 
catalytic (c) ssubunits
PALA +/-
 
catalytic loops 230-245 (yellow)
(cr2c) + 4 PALA / + 2 CTP 
 
c3+/-  3 PALA 
 
surface catalytic sites  
c3+/-3 PALA 
 
"Relaxed" (R) Conformation
 catalytic (c) subunits + PALA ( transition state analog)
"Tense" (T) Conformation
regulatory
(r) subunits + CTP (negative regulatory inhibitor)
@ Duane Sears July 26, 2019