Hemoglobin's Tetravalent Equilibrium Reaction with
Oxygen as Compared to Myoglobin's Monovalent Reaction

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Downloading the CDF activity file: After insalling the CDF Player, CLICK HERE to download and open the CDF activity file that displays different interative monovalent acid/base titration plots like the static screen captured image from this exercise as shown below.

Rectangular hyperbolic and Hill plot analysis oxygen binding to Hb and Mb (with caption narrative): Rectangular hyperbolic plot analysis (top) and Hill plot analysis (bottom) of the O2 binding reactions of tetravalent hemoglobin (Hb) and monovalent myoglobin (Mb) are compared according to variations (adjusted with sliders) in the ambient pO2 (the partial pressure of oxygen, pH, and theoretical values for the Hill coefficient (n) of Hb.




Nicholas Clayton and Duane W. Sears (c) 2011, University of California Santa Barbara.